Dosageescription:
Learn everything about Chlorpheniramine Maleate BP β its uses, mechanism of action, dosage, side effects, precautions, and FAQs for safe allergy relief.
Introduction
Chlorpheniramine Maleate BP is a widely used antihistamine medication, commonly prescribed for the treatment of allergic conditions such as hay fever, runny nose, watery eyes, skin allergies, and itching. It belongs to the group of first-generation antihistamines, which are effective but may cause drowsiness.
It is often available as tablets, syrups, and injections, depending on the condition being treated.
What is Chlorpheniramine Maleate BP Used For?
Chlorpheniramine Maleate BP is mainly used for:
Allergic rhinitis (hay fever)
Common cold symptoms (sneezing, runny nose)
Urticaria (hives)
Skin allergies and itching
Conjunctivitis due to allergies
Insect bites and stings
Asthma-related allergic symptoms (in combination with other medicines)
How Does Chlorpheniramine Maleate BP Work?
Chlorpheniramine works by blocking histamine H1 receptors in the body.
Histamine is a natural substance released during an allergic reaction that causes itching, sneezing, watery eyes, and runny nose.
By preventing histamine from binding to its receptors, Chlorpheniramine reduces allergy symptoms effectively.
However, as a first-generation antihistamine, it may also cross the blood-brain barrier, causing drowsiness and sedation.
Dosage & Usage
Adults: 4 mg every 4β6 hours (maximum 24 mg per day).
Children (6β12 years): 2 mg every 4β6 hours (maximum 12 mg per day).
Children (2β6 years): 1 mg every 4β6 hours (maximum 6 mg per day).
Children under 2 years: Use only if prescribed by a doctor.
Dosage may vary depending on formulation (tablet, syrup, or injection) and medical condition. Always follow a physicianβs advice.
Side Effects
Common Side Effects:
Drowsiness
Dry mouth, throat, or nose
Dizziness
Blurred vision
Constipation
Serious Side Effects (rare):
Difficulty urinating
Confusion (especially in elderly patients)
Fast or irregular heartbeat
Allergic reaction (rash, swelling, difficulty breathing)
Precautions
Avoid alcohol or sedatives while taking Chlorpheniramine, as it may increase drowsiness.
Patients with asthma, glaucoma, peptic ulcer, enlarged prostate, or heart problems should consult a doctor before use.
Not recommended for pregnant or breastfeeding women unless prescribed.
May impair alertness β avoid driving or operating machinery after taking it.
Frequently Asked Questions (FAQ)
1. Is Chlorpheniramine Maleate BP safe for children?
Answer: Yes, it can be given to children above 2 years, but only in recommended doses. Infants and toddlers should take it only if prescribed by a doctor.
2. Does it make you sleepy?
Answer: Yes, Chlorpheniramine is a first-generation antihistamine that commonly causes drowsiness. This effect may be stronger if combined with alcohol or sedatives.
3. Can I take Chlorpheniramine for the common cold?
Answer: Yes, it helps reduce runny nose, sneezing, and watery eyes associated with the common cold. However, it does not cure viral infections.
4. How long does it take to work?
Answer: Relief usually starts within 30 minutes to 1 hour, and the effect lasts for about 4β6 hours.
5. Is long-term use safe?
Answer: Prolonged use is generally not recommended without medical supervision, as it may cause tolerance and unwanted side effects such as dry mouth, constipation, or drowsiness.
Conclusion
Chlorpheniramine Maleate BP is a safe and effective antihistamine when used properly. It provides quick relief from allergy symptoms such as sneezing, itching, and runny nose. However, because it may cause drowsiness, patients should be cautious when driving, working, or combining it with other sedatives. Always use under the guidance of a healthcare professional.


